Licensing opportunities
Here is an overview of Inven2s existing licensing opportunities divided into eight technology categories. Each licensing opportunity is described in more detail featuring business opportunity, technology, advantages, contact information and other relevant information.
3D cell culture model for differentiated natural osteocytes without artificial additives
BUSINESS OPPORTUNITY Well-functioning in-vitro models of human osteocytes are lacking. Scientists at the University of Oslo and Oslo ... Read more
Novel applications of VAS for treatment and prevention of cardiorenal damage in HFpEF
Business opportunity Scientists from Oslo University Hospital and University of Oslo observed that Vastiras (VAS), a cardiac hormone ... Read more
EpCaM-targeted immunotoxin for advanced cancers
Scientists at Oslo University Hospital have developed an immunotoxin, MOC31PE, comprising a full-length murine antibody against the ... Read more
CHRONOS – early detection of brain-tumor progression
Business opportunity Brain tumors are one of the deadliest forms of cancer and the primary goal of treatment is simply to decelerate ... Read more
Non-Invasive Diagnostic Tool for Heart Failure
Business opportunity Heart failure is one of the most prevalent heart diseases, affecting over 64 million people worldwide, and has a ... Read more
Solid Electrolyte Interface Stabilizers for Li-ion batteries
Business opportunity Leading scientists at the Dept. of Chemistry, Univ. of Oslo have developed additives for silicon ... Read more
CAR-T for p95HER2-positive breast cancer patients resistant to antibody treatments targeting HER2
Business opportunity About 50% of human epidermal growth factor receptor 2 (HER2)-positive tumors express p95HER2, a known ... Read more
TAM Targeting Nanobody (Immunocytokine IL-15) for Solid Tumours
The present invention involves a recombinant Nanobody (llama antibody) drug that recognizes a surface molecule (CD206) that is expressed on tumour associated macrophages. Read more
A urine test for detection and monitoring of bladder cancer
BUSINESS OPPORTUNITY Scientists at Oslo University Hospital are developing a urine based test, addressing a major unmet need for ... Read more
Scalable Pump-less organ-on-a-chip platform with directed flow
Business opportunity Scientists at the University of Oslo (Norway) have developed an innovative, scalable directional pump-less ... Read more
siRNA drug targeting MTHFD2 for treatment of prostate cancer
Scientists at University of Oslo have identified a mitochondrial enzyme, MTHFD2, as a potential therapeutic target in prostate cancer ... Read more
MIGS glaucoma device with multiple channels
BACKGROUND Improved management of glaucoma Glaucoma is a multifactorial optic neuropathy characterized by progressive damage to ... Read more
MicroRNA therapeutics for osteoarthritis and other inflammatory diseases
Our team at Oslo University Hospital and University of Oslo has found a potent immune regulatory microRNA harbouring a potential to ... Read more
STEAP1 CAR for metastatic prostate cancer
Business opportunity Scientists at Oslo University Hospital (Norway) have developed a new chimeric antigen receptor (CAR) targeting ... Read more
TCR sequencing method for diagnosing celiac disease without gluten challenge or biopsy
BUSINESS OPPORTUNITY Scientists at Oslo University Hospital and University of Oslo have identified a repertoire of celiac disease ... Read more
HLA-II targeting vaccines
Our team at Oslo University Hospital and University of Oslo has developed a novel targeting sequence that allows for direct targeting ... Read more
Circulating mitochondrial DNA (mtDNA) variants to predict metastatic progression of rectal cancer
Executive summary Leading scientists and clinicians at the Akershus University Hospital (Norway) have identified mitochondrial DNA ... Read more
AI-based segmentation of vascular structures
Business opportunity Scientists at the Inst. of Clin. Med., Univ. of Oslo, Akershus Univ. Hospital, and Faculty of Med., Univ. of ... Read more
Improving HDR by fusion of novel DNA repair proteins to CRISPR-Cas9
Business opportunity Scientists from the University in Oslo, Karolinska Institute in Stockholm and University in Helsinki have ... Read more
FLOWS
BUSINESS OPPORTUNITY Inven2 seeks interested development partners and/or licensees for the technology. Exclusive license limited to a ... Read more
Dual CAR T-cell targeting CD19/Ig-kappa for safer Lymphoma therapy
BUSINESS OPPORTUNITY This new CAR T-cell can be developed to treat children and adults with B cell lymphoma. Inven2 is seeking to ... Read more
TCR-CAR Allogeneic Platform Technology (Solid Tumours/Hematological Cancer)
Figure 1 - Invention: A soluble TCR molecule was fused to the signalling domain of a CAR molecule. Figure 2 - Efficacy: Lysis ... Read more
CAR T-cell Therapy for Osteosarcoma (OSCAR)
Business opportunity This technology has the possibility to effectively treat children and adults with metastatic osteosarcoma (bone ... Read more
Novel therapy for currently untreatable hypertension
Business opportunity Resistant hypertension (RHT) is a frequent disease and causes premature morbidity and death. RHT is defined as ... Read more
BioZEment: Low CO2 emission building material employing bacterial metabolism
The BioZEment concept is based on dissolution and re-crystallization of calcium carbonate induced by selected, non-pathogenic bacterial strains. Read more
Novel design of fuel-cells and electrolysers
A proton ceramic electrochemical cell designed for a simplified one-step manufacturing of a whole structure with one single material only and post infiltration of the electrode materials. Read more
Continuous monitoring of patients with ventricular assist device
Researchers at Oslo University Hospital have developed a method with an accelerometer attached to an LVAD. Read more
Needle-I – “seeing” what tissue types surround a needle tip
A method to discriminate nerve tissue from other tissue types and detect intraneural needle placement in peripherial nerve blocks with very high sensitivity and specificity (ROC=97% in animal model). Clinical studies in humans are needed to confirm the results. Read more
Space weather forecast for improved navigation precision
a model that can predict the most severe instances of ionospheric disturbance on Global Navigation Satellite Systems (GPS, Galilieo, etc). Read more
Faster and better ultrasound imaging
A software beamforming method that reduces the ultrasound data processing time and complexity dramatically. Read more
Very high production rates of medical radio isotopes with cyclotrons
A target holder, target formulation technology, and a cyclotron production process allowing intense target irradiation and very high output of medical radio isotopes. Read more
Therapeutic regulation of WNT/YAP-signaling through a potent and specific tankyrase inhibitor
A class of novel WNT/YAP inhibitor compounds exhibiting high specificity for tankyrase and demonstrated proof of concept in mouse models for several cancer indications. Read more
Prediagnostic RNA biomarkers for early detection of lung cancer
Leading scientists at the Cancer Registry of Norway and Oslo University Hospital have identified prediagnostic serum RNA biomarkers for early detection of lung cancer (LC). Read more
Principle for modifying gut microbiota
A homogenized and freeze-dried bacterial that will used as an animal feed additive to prevent inflammation and improve gut health. Read more
Sensitive ChIP-seq method for the study of single cells and small pools of cells
A sensitive ChIP-seq method for the study of single cells and small pools of cells to reveal where specific proteins or modified histones are bound throughout the genome. Read more
TaME-seq: for detection of viral variation and integration
Application: TaME-seq (tagmentation-assisted multiplex PCR enrichment sequencing) is a tool for detection of viral variation and ... Read more
An optimized engineered albumin for half-life extension and mucosal delivery of biologics
An engineered human albumin variant with extended in vivo half-life. Read more
AlbuVAX – A novel mucosal delivery technology for subunit vaccines
A novel technology for enhanced uptake of subunit vaccines across mucosal barriers. Read more
A versatile improved antibody Fc technology platform
A unique and versatile antibody Fc technology platform (“REW”). Read more
MetaGate – For fast and simple analysis of complex single-cell data
Recent advances in flow and mass cytometers have enabled assessment of more parameters. Read more
AnaConDebt – Analysis of Contagious technical Debt
Technical debt in software development consists of sub-optimal design solutions that are beneficial in the short term, but create costly negative impact in the long run, e.g. costly maintenance changes and impossibility to evolve the system. Read more
Highly Epitaxial Metallic Oxides at Low Thermal Budget
A production method for materials with very high conductivity targeting the key challenges in the electronics industry Read more
High data-rate wireless communication for deep medical implants
A prototype system for wireless capsule endoscopy utilizing radio frequency backscatter communication is developed. Read more
Extended Focus – Super-resolution microscopy
In order to capture rapid cellular events without disrupting processes due to photodamage and/or bleaching, cell biologists usually compromise on some imaging parameters, for instance, by not reaching Nyquist sampling of the Z-stacks or by lowering laser power, which worsen the signal-to-noise ratio. Read more
ELLA – Analysis tool for clinical interpretation of genetic variants
ELLA is a software tool for clinical interpretation of genetic variants that is developed and in use at the Department of Medical Genetics at Oslo University Hospital, Norway. Read more
