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CA125 domain of MUC16 as a novel target to treat ovarian cancer

Background Ovarian cancer is the leading cause of death from gynaecological malignancies in the Western world. CAR-T cell therapy has ... Read more

Switch receptor for use in adoptive cell therapy

Business opportunity Therapy employing T cells modified with chimeric antigen receptors (CARs) is effective in hematological ... Read more

DogBiTE to treat canine osteosarcoma

Background Dogs spontaneously develop cancer just like humans. Canine osteosarcoma is an aggressive bone tumour with high rate of ... Read more

Neoantigen-specific TCR, Radium-1, for treatment of solid malignancies

Background Colorectal cancer (CRC) is the third most common cancer worldwide. Despite fair survival for localized CRC, metastatic CRC ... Read more


A paradigm shift in cancer therapy – using mitochondria-powered chemiluminescence to non-invasively treat inaccessible ... Read more

Biomarker for de-escalating adjuvant chemotherapy in breast cancer

BUSINESS OPPORTUNITY Leading scientists at the Oslo University Hospital have identified a unique biomarker in patients with ... Read more

Multilumen glaucoma surgery stent

Background Glaucoma is a multifactorial optic neuropathy characterized by progressive damage to the optic nerve, which results in the ... Read more

Novel peptide with very strong endotoxin binding

BUSINESS OPPORTUNITY Lipopolysaccharides (LPS) or endotoxins are an important part of the outer membrane of Gram-negative bacteria. ... Read more

Rapeseed trait reducing seed loss

BUSINESS OPPORTUNITY Rapeseed (canola, Brassica napus) is the second largest oil crop in the world. Accounting for about 16% of the ... Read more

Tuned CAR-T cells – a platform technology

Poor persistence of the T-cell product represents an important challenge with CAR-T cell therapy. This is often due to constitutive ... Read more

TANDEMAb: IgA-IgG fusions with tailored effector functions

Business opportunity Monoclonal antibodies have revolutionized treatment, especially for cancer and autoimmune diseases. However, a ... Read more

A neural network based denoising system

Business Opportunity Scientists from the Institute for Experimental Medical Research at the University of Oslo are developing ... Read more

Bio-engineered palladium nanoparticles

Business opportunity Palladium nanoparticles (Pd NPs) have a wide range of applications in for example catalysis, sensors, fuel cells ... Read more

3D cell culture model for differentiated natural osteocytes without artificial additives

BUSINESS OPPORTUNITY Well-functioning in-vitro models of human osteocytes are lacking. Scientists at the University of Oslo and Oslo ... Read more

Novel applications of VAS for treatment and prevention of cardiorenal damage in HFpEF

Business opportunity Scientists from Oslo University Hospital and University of Oslo observed that Vastiras (VAS), a cardiac hormone ... Read more

Early detection of brain-tumor progression

Business opportunity Brain tumors are one of the deadliest forms of cancer and the primary goal of treatment is simply to decelerate ... Read more

Non-Invasive Diagnostic Tool for Heart Failure

Business opportunity Heart failure is one of the most prevalent heart diseases, affecting over 64 million people worldwide, and has a ... Read more

Solid Electrolyte Interface Stabilizers for Li-ion batteries

Business opportunity Leading scientists at the Dept. of Chemistry, Univ. of Oslo have developed additives for silicon ... Read more

CAR-T for p95HER2-positive breast cancer patients resistant to antibody treatments targeting HER2

Business opportunity About 50% of human epidermal growth factor receptor 2 (HER2)-positive tumors express p95HER2, a known ... Read more

A urine test for detection and monitoring of bladder cancer

BUSINESS OPPORTUNITY Scientists at Oslo University Hospital are developing a urine based test, addressing a major unmet need for ... Read more

Scalable Pump-less organ-on-a-chip platform with directed flow

  Business opportunity Scientists at the University of Oslo (Norway) have developed an innovative, scalable directional ... Read more

siRNA drug targeting MTHFD2 for treatment of prostate cancer

Scientists at University of Oslo have identified a mitochondrial enzyme, MTHFD2, as a potential therapeutic target in prostate cancer ... Read more

STEAP1 CAR for metastatic prostate cancer

Business opportunity Scientists at Oslo University Hospital (Norway) have developed a new chimeric antigen receptor (CAR) targeting ... Read more

HLA-II targeting vaccines

Our team at Oslo University Hospital and University of Oslo has developed a novel targeting sequence that allows for direct targeting ... Read more

AI-based segmentation of vascular structures

Business opportunity Scientists at the Inst. of Clin. Med., Univ. of Oslo, Akershus Univ. Hospital, and Faculty of Med., Univ. of ... Read more

CAR T-cell Therapy for Osteosarcoma (OSCAR)

Business opportunity The present technology has the potential to effectively treat children and adults with metastatic osteosarcoma ... Read more

Novel therapy for currently untreatable hypertension

Business opportunity Resistant hypertension (RHT) is a frequent disease and causes premature morbidity and death. RHT is defined as ... Read more

Needle-I – “seeing” what tissue types surround a needle tip

A method to discriminate nerve tissue from other tissue types and detect intraneural needle placement in peripherial nerve blocks with very high sensitivity and specificity (ROC=97% in animal model). Clinical studies in humans are needed to confirm the results. Read more

Faster and better image processing in radar, sonar and ultrasound

A software beamforming method that reduces the ultrasound data processing time and complexity dramatically. Read more

Very high production rates of medical radio isotopes with cyclotrons

A target holder, target formulation technology, and a cyclotron production process allowing intense target irradiation and very high output of medical radio isotopes. Read more

Therapeutic regulation of WNT/YAP-signaling through a potent and specific tankyrase inhibitor

A class of novel WNT/YAP inhibitor compounds exhibiting high specificity for tankyrase and demonstrated proof of concept in mouse models for several cancer indications. Read more

Prediagnostic RNA biomarkers for early detection of lung cancer

Leading scientists at the Cancer Registry of Norway and Oslo University Hospital have identified prediagnostic serum RNA biomarkers for early detection of lung cancer (LC). Read more

Sensitive ChIP-seq method for the study of single cells and small pools of cells

A sensitive ChIP-seq method for the study of single cells and small pools of cells to reveal where specific proteins or modified histones are bound throughout the genome. Read more

An optimized engineered albumin for half-life extension and mucosal delivery of biologics

An engineered human albumin variant with extended in vivo half-life. Read more

AlbuVAX – A novel mucosal delivery technology for subunit vaccines

A novel technology for enhanced uptake of subunit vaccines across mucosal barriers. Read more

A versatile improved antibody Fc technology platform

A unique and versatile antibody Fc technology platform (“REW”). Read more

MetaGate – For fast and simple analysis of complex single-cell data

Recent advances in flow and mass cytometers have enabled assessment of more parameters. Read more

AnaConDebt – Analysis of Contagious technical Debt

Technical debt in software development consists of sub-optimal design solutions that are beneficial in the short term, but create costly negative impact in the long run, e.g. costly maintenance changes and impossibility to evolve the system. Read more

Highly Epitaxial Metallic Oxides at Low Thermal Budget

A production method for materials with very high conductivity targeting the key challenges in the electronics industry Read more