Tuned CAR-T cells – a platform technology

Poor persistence of the T-cell product represents an important challenge with CAR-T cell therapy. This is often due to constitutive activity of the CAR leading to T cells exhaustion before a therapeutic effect can be achieved. To address this challenge, an original...

STEAP1 CAR for metastatic prostate cancer

Business opportunity Scientists at Oslo University Hospital (Norway) have developed a new chimeric antigen receptor (CAR) targeting STEAP1 positive cells. STEAP1 is expressed in about 90% of prostate cancers, and subgroups of other malignancies, and it is an...